Orthostatic hypotension, diabetes, and falling in older patients: a cross-sectional study

Br J Gen Pract. 2012 Oct;62(603):e696-702. doi: 10.3399/bjgp12X656838.

Abstract

Background: Although orthostatic hypotension (OH) is more prevalent in old age, and in patients with diabetes, the prevalence of OH in older patients with type 2 diabetes mellitus is unknown.

Aim: To establish the prevalence of OH, and its association with falling, in home-dwelling older participants with and without type 2 diabetes.

Design and setting: A cross-sectional study in primary care in the Netherlands.

Method: A total of 352 patients with type 2 diabetes, and 211 without participated in this study. OH was defined as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic after either 1 or 3 minutes in an upright position. Feelings of dizziness, light-headedness, or faintness during the standing period were documented as orthostatic complaints. Fall risk was assessed with a validated risk profile instrument.

Results: The prevalence of OH was 28% (95% CI = 24% to 33%) and 18% (95% CI = 13% to 23%) in participants with and without type 2 diabetes, respectively. OH was not related to falling, while the presence of orthostatic complaints in itself was associated with both previous fall incidents as well as a high fall risk, even after adjustment for OH. The adjusted odds ratios were 1.65 (95% CI = 1.00 to 2.72) and 8.21 (95% CI = 4.17 to 16.19), respectively.

Conclusion: OH is highly prevalent in home-dwelling older people with and without type 2 diabetes. Those with orthostatic complaints had an increased risk for falling, whereas those with OH were not.

MeSH terms

  • Accidental Falls / statistics & numerical data*
  • Aged
  • Blood Pressure Determination
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Female
  • General Practice / statistics & numerical data*
  • Humans
  • Hypotension, Orthostatic / epidemiology*
  • Hypotension, Orthostatic / physiopathology
  • Independent Living
  • Logistic Models
  • Male
  • Netherlands / epidemiology
  • Odds Ratio
  • Prevalence
  • Risk Factors