Genetically epileptic rats show a pronounced intermediate stage of sleep

Physiol Behav. 1990 Jan;47(1):213-5. doi: 10.1016/0031-9384(90)90063-a.

Abstract

Rats of the genetically epileptic WAG/Rij strain show a more long-lasting intermediate stage of sleep compared to rats of the Wistar strain. Therefore the WAG/Rij strain provides a privileged model for studying this stage of sleep. On the other hand, the percentage of paradoxical sleep in WAG/Rij rats is lower than in Wistar rats, for the reason that the intermediate stage in WAG/Rij rats is less frequently followed by paradoxical sleep and more frequently by slow wave sleep and especially by arousals. It is speculated that the epileptic rats encounter a greater difficulty in entering into paradoxical sleep.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Disease Models, Animal
  • Epilepsy / physiopathology*
  • Male
  • Rats
  • Rats, Inbred Strains
  • Sleep Stages / physiology*