Acquired von Willebrand syndrome in a patient with monoclonal gammopathy of undetermined significance

Blood Coagul Fibrinolysis. 2013 Jun;24(4):430-2. doi: 10.1097/MBC.0b013e32835bfdde.

Abstract

Acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder that typically presents as mucocutaneous bleeding in individuals with no personal or family history of bleeding disorder. Here we present a case in which a patient presented with profound epistaxis and was found to have AVWS in the setting of monoclonal gammopathy of undetermined significance (MGUS).

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Epistaxis / blood
  • Epistaxis / complications*
  • Epistaxis / pathology
  • Factor VIII / metabolism
  • Humans
  • Male
  • Monoclonal Gammopathy of Undetermined Significance / blood
  • Monoclonal Gammopathy of Undetermined Significance / complications*
  • Monoclonal Gammopathy of Undetermined Significance / pathology
  • Syndrome
  • von Willebrand Diseases / blood
  • von Willebrand Diseases / complications*
  • von Willebrand Diseases / pathology
  • von Willebrand Factor / metabolism

Substances

  • von Willebrand Factor
  • Factor VIII