Clonal dissemination of Pseudomonas aeruginosa isolates producing extended-spectrum β-lactamase SHV-2a

J Clin Microbiol. 2013 Feb;51(2):673-5. doi: 10.1128/JCM.02313-12. Epub 2012 Dec 12.

Abstract

From January to December 2011, 24 Pseudomonas aeruginosa strains producing the extended-spectrum β-lactamase SHV-2a were identified in 13 hospitals in France. With one exception, all the strains belonged to the same clone. Double-disk synergy tests with cefepime and clavulanate were able to detect all the SHV-2a-positive isolates.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Typing Techniques
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • France / epidemiology
  • Hospitals
  • Humans
  • Microbial Sensitivity Tests
  • Pseudomonas Infections / epidemiology
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa / classification*
  • Pseudomonas aeruginosa / drug effects
  • Pseudomonas aeruginosa / genetics
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • beta-lactamase SHV-12
  • beta-lactamase SHV-2a
  • beta-Lactamases