Coumarin-DPA-Cu(II) as a chemosensing ensemble towards histidine determination in urine and serum

Org Biomol Chem. 2013 Feb 7;11(5):717-20. doi: 10.1039/c2ob26955d. Epub 2012 Dec 13.

Abstract

An ensemble-based fluorescent sensor HS-1 + Cu(2+) for detection of histidine is reported. Complex HS-1 + Cu(2+) sensitively senses histidine at pH 7.4 in aqueous media. The quantitative determination of histidine in urine and fetal calf serum is also conducted.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amines / chemistry*
  • Animals
  • Copper / chemistry*
  • Coumarins / chemistry*
  • Fluorescent Dyes / chemistry*
  • Histidine / blood*
  • Histidine / urine*
  • Humans
  • Picolinic Acids / chemistry*
  • Sensitivity and Specificity
  • Spectrometry, Fluorescence / methods

Substances

  • 2,2'-dipicolylamine
  • Amines
  • Coumarins
  • Fluorescent Dyes
  • Picolinic Acids
  • Histidine
  • Copper
  • coumarin