The efficacy of 8% Arginine-CaCO₃ applications on dentine hypersensitivity following periodontal therapy: a clinical and scanning electron microscopic study

Med Oral Patol Oral Cir Bucal. 2013 Mar 1;18(2):e298-305. doi: 10.4317/medoral.17990.

Abstract

Objectives: Periodontal therapy is one of the etiological factors of dentine hypersensitivity (DH). This study aimed to evaluate the efficacy of %8Arginine-CaCO₃ on DH that affects patients after periodontal treatment.

Study design: Seventy-one teeth from the volunteers (n=36) with history of DH caused by periodontal therapy were included in this study, and randomly divided into two groups: group-1, who received 8%Arginine-CaCO₃ and group-2, who received 1.23%NaF-gel. The clinical indices were recorded at first visit.DH was evaluated by using tactile, air-blast, and thermal stimuli. The subject's response was recorded at baseline, immediately (Day-0) and one month after the application.

Results and conclusions: The results were statistically analyzed, and it was found that 8% Arginine-CaCO₃ treatment was more effective than 1.23% NaF-gel at time intervals. Sensitivity score differences between the groups were statistically significant at Day-28. The 8% Arginine-CaCO₃ group exhibited statistically significant reduction in DH on three stimuli at baseline to Day-28. It was concluded that 8% Arginine-CaCO₃ is more effective than 1.23% NaF-gel in reduction of patients' pain.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Arginine / administration & dosage*
  • Calcium Carbonate / administration & dosage*
  • Dentin Sensitivity / drug therapy*
  • Dentin Sensitivity / pathology
  • Double-Blind Method
  • Drug Combinations
  • Female
  • Humans
  • Microscopy, Electron, Scanning
  • Periodontal Diseases / therapy

Substances

  • Drug Combinations
  • Arginine
  • Calcium Carbonate