Abstract
Acinetobacter baumannii is a Gram-negative bacterium which emerged as a significant nosocomial pathogen worldwide. To investigate the molecular basis of the tigecycline-resistant mechanism, we determined the genome sequences of two multidrug-resistant A. baumannii strains isolated from a patient before and after treatment with tigecycline.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections / drug therapy
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Acinetobacter Infections / microbiology*
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Acinetobacter baumannii / drug effects
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Acinetobacter baumannii / genetics*
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Acinetobacter baumannii / isolation & purification
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Anti-Bacterial Agents / therapeutic use*
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Cross Infection / drug therapy
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Cross Infection / microbiology
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DNA, Bacterial / genetics
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Drug Resistance, Multiple, Bacterial / genetics
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Genome, Bacterial*
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Humans
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Interspersed Repetitive Sequences
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Minocycline / analogs & derivatives*
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Minocycline / therapeutic use
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Molecular Sequence Data
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Sequence Analysis, DNA
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Tigecycline
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Tigecycline
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Minocycline
Associated data
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GENBANK/AMGR00000000
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GENBANK/AMGR01000000
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GENBANK/AMGS00000000
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GENBANK/AMGS01000000