Long-term results of thoracoscopic thymectomy for thymoma without myasthenia gravis

J Int Med Res. 2012;40(5):1973-81. doi: 10.1177/030006051204000539.

Abstract

Objective: To compare the feasibility and safety of thoracoscopic thymectomy with conventional sternotomy thymectomy for thymoma without myasthenia gravis.

Methods: Data from 70 patients diagnosed with thymoma, who underwent thoracoscopic thymectomy (n = 25, Group T) or sternotomy thymectomy (n = 45, Group S) between March 2002 and March 2008, were retrospectively evaluated.

Results: Mean follow-up durations were 78.0 ± 21.9 months and 70.0 ± 23.6 months in Groups T and S, respectively. No deaths occurred in Group T; seven deaths occurred in Group S, all > 1 month post follow-up. Durations of chest intubation and hospitalization were significantly shorter in Group T than in Group S. No significant between-group difference in the incidence of operative complications was observed. Tumour recurrence-free rates at 5 and 7 years postsurgery were 96% (both years) in Group T and 95% (both years) in Group S.

Conclusions: Long-term follow-up indicates that thoracoscopic thymectomy for thymoma without myasthenia gravis is effective and is well tolerated, and associated with low rates of operative complications and recurrence.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Combined Modality Therapy
  • Disease-Free Survival
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Myasthenia Gravis
  • Neoplasm Recurrence, Local / prevention & control*
  • Radiography
  • Retrospective Studies
  • Sternotomy
  • Thoracoscopy
  • Thymectomy
  • Thymoma / diagnostic imaging
  • Thymoma / mortality
  • Thymoma / surgery*
  • Thymus Neoplasms / diagnostic imaging
  • Thymus Neoplasms / mortality
  • Thymus Neoplasms / surgery*
  • Young Adult