Community-associated methicillin-resistant Staphylococcus aureus necrotizing pneumonia in a healthy neonate

J Microbiol Immunol Infect. 2014 Dec;47(6):555-7. doi: 10.1016/j.jmii.2012.07.001. Epub 2012 Nov 20.

Abstract

The number of cases of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia has increased since the late 1990s, with skin and soft tissue infections predominant among neonates. Herein, we present a rare case of CA-MRSA necrotizing pneumonia with empyema following respiratory syncytial virus (RSV) infection in a healthy neonate. Despite prompt vancomycin treatment, the disease worsened and finally we had to perform pneumonectomy. This case highlights the possibility of emerging CA-MRSA-related invasive disease among neonates.

Keywords: Community-associated methicillin-resistant Staphylococcus aureus; Neonate; Pneumonia.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Community-Acquired Infections / diagnosis*
  • Community-Acquired Infections / microbiology*
  • Community-Acquired Infections / pathology
  • Community-Acquired Infections / therapy
  • Empyema / diagnosis
  • Empyema / etiology
  • Empyema / pathology
  • Female
  • Humans
  • Infant, Newborn
  • Lung / pathology*
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification*
  • Necrosis / pathology*
  • Pneumonectomy
  • Pneumonia, Staphylococcal / complications
  • Pneumonia, Staphylococcal / diagnosis*
  • Pneumonia, Staphylococcal / microbiology*
  • Pneumonia, Staphylococcal / pathology
  • Respiratory Syncytial Virus Infections / diagnosis
  • Respiratory Syncytial Virus Infections / pathology
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Vancomycin