Noncontrast-enhanced renal angiography using multiple inversion recovery and alternating TR balanced steady-state free precession

Magn Reson Med. 2013 Aug;70(2):527-36. doi: 10.1002/mrm.24480. Epub 2012 Nov 21.

Abstract

Noncontrast-enhanced renal angiography techniques based on balanced steady-state free precession avoid external contrast agents, take advantage of high inherent blood signal from the T 2 / T 1 contrast mechanism, and have short steady-state free precession acquisition times. However, background suppression is limited; inflow times are inflexible; labeling region is difficult to define when tagging arterial flow; and scan times are long. To overcome these limitations, we propose the use of multiple inversion recovery preparatory pulses combined with alternating pulse repetition time balanced steady-state free precession to produce renal angiograms. Multiple inversion recovery uses selective spatial saturation followed by four nonselective inversion recovery pulses to concurrently null a wide range of background T 1 species while allowing for adjustable inflow times; alternating pulse repetition time steady-state free precession maintains vessel contrast and provides added fat suppression. The high level of suppression enables imaging in three-dimensional as well as projective two-dimensional formats, the latter of which has a scan time as short as one heartbeat. In vivo studies at 1.5 T demonstrate the superior vessel contrast of this technique.

Keywords: SSFPangiography; angiography; multiple inversion recovery; noncontrast-enhanced angiography; projective imaging.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Algorithms*
  • Blood Flow Velocity / physiology
  • Contrast Media
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Renal Artery / anatomy & histology*
  • Renal Artery / physiology*
  • Renal Circulation / physiology*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Young Adult

Substances

  • Contrast Media