Abstract
Through substituting two canonical base pairs of a streptavidin-binding aptamer with T-T mismatched base pairs, a new aptamer was constructed. Its binding ability could be controlled by Hg(2+) through the formation of T-Hg-T metal-base pairs.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aptamers, Nucleotide / chemistry
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Aptamers, Nucleotide / metabolism*
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Base Pair Mismatch
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Hemin / chemistry
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Ions / chemistry
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Mercury / chemistry*
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Peroxidases / metabolism
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Spectrometry, Fluorescence
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Streptavidin / metabolism*
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Thymidine / chemistry
Substances
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Aptamers, Nucleotide
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Ions
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Hemin
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Streptavidin
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Peroxidases
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Mercury
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Thymidine