Inversion time prolongation at late enhancement cardiac MRI in a myeloma patient

Diagn Interv Radiol. 2012 Nov-Dec;18(6):552-4. doi: 10.4261/1305-3825.DIR.5923-12.2.

Abstract

A patient undergoing chemotherapy for multiple myeloma had a sudden onset of heart failure. Cardiac magnetic resonance was performed after echocardiography to rule out myocardial late enhancement, which was not detected. In- terestingly, the inversion time of the T1-weighted inversion recovery late enhancement sequence needed to be significantly increased (from the usual 250-300 to 490 ms) to obtain diagnostic images. This report presents the clinical case of this patient, and discusses potential implications.

Publication types

  • Case Reports

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Contrast Media*
  • Diagnosis, Differential
  • Echocardiography / methods
  • Fatal Outcome
  • Heart Failure / complications*
  • Heart Failure / diagnosis*
  • Humans
  • Image Enhancement / methods*
  • Image Processing, Computer-Assisted / methods
  • Lenalidomide
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meglumine
  • Middle Aged
  • Multiple Myeloma / complications*
  • Multiple Myeloma / drug therapy
  • Myocardium / pathology
  • Organometallic Compounds
  • Thalidomide / analogs & derivatives
  • Thalidomide / therapeutic use

Substances

  • Angiogenesis Inhibitors
  • Contrast Media
  • Organometallic Compounds
  • Thalidomide
  • Meglumine
  • Lenalidomide
  • gadoterate meglumine