Measurement of the base number of DNA using a special calliper made of a split G-quadruplex

Jinbo Zhu; Libing Zhang; Erkang Wang

doi:10.1039/c2cc36693b

Measurement of the base number of DNA using a special calliper made of a split G-quadruplex

Chem Commun (Camb). 2012 Dec 21;48(98):11990-2. doi: 10.1039/c2cc36693b.

Authors

Jinbo Zhu¹, Libing Zhang, Erkang Wang

Affiliation

¹ State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.

PMID: 23133833
DOI: 10.1039/c2cc36693b

Abstract

A special DNA calliper made of a split G-quadruplex was constructed to measure the length of DNA in a single-digit base number range between two selected sequences. The enhanced fluorescence of PPIX changed with the distance between two G-rich segments.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Circular Dichroism
DNA / chemistry*
Fluorescence
G-Quadruplexes*
Protoporphyrins / chemistry
Spectrometry, Fluorescence

Substances

Protoporphyrins
DNA
protoporphyrin IX