Comparative study of 15% TCA peel versus 35% glycolic acid peel for the treatment of melasma

Indian Dermatol Online J. 2012 May;3(2):109-13. doi: 10.4103/2229-5178.96702.

Abstract

Background: Chemical peels are the mainstay of a cosmetic practitioner's armamentarium because they can be used to treat some skin disorders and can provide aesthetic benefit.

Objectives: To compare 15% TCA peel and 35% glycolic acid peel for the treatment of melasma.

Material and methods: We selected 30 participants of melasma aged between 20 and 50 years from the dermatology outpatient department and treated equal numbers with 15% TCA and 35% glycolic acid.

Results: Subjective response as graded by the patient showed good or very good response in 70% participants in the glycolic acid group and 64% in the TCA group.

Conclusions: There was statistically insignificant difference in the efficacy between the two groups for the treatment of melasma.

Keywords: Acne scarring; TCA; glycolic acid; melasma; peels; photoaging.