The use of dermabond® as an adjunct to wound closure after total knee arthroplasty: examining immediate post-operative wound drainage

J Arthroplasty. 2013 Apr;28(4):553-6. doi: 10.1016/j.arth.2012.07.038. Epub 2012 Oct 29.

Abstract

Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001).

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Knee / methods*
  • Cyanoacrylates*
  • Drainage*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Period
  • Prospective Studies
  • Single-Blind Method
  • Time Factors
  • Tissue Adhesives*
  • Wound Closure Techniques*
  • Wound Healing

Substances

  • Cyanoacrylates
  • Tissue Adhesives
  • octyl 2-cyanoacrylate