A hybrid operating room is a space that meets all the stringent requirements of an operating room harbouring the facilities of an interventional radiology or cardiology room. This technical innovation facilitates complex endovascular and hybrid operations in a sterile environment. The high-end imaging technique with the ability to perform three-dimensional reconstructions will lead to improved quality of endovascular operations. Moreover, this technique enables physicians to explore and extend the boundaries not only of cardiovascular but also of navigated minimally invasive surgical techniques.