Palladium-catalyzed desulfitative arylation by C-O bond cleavage of aryl triflates with sodium arylsulfinates

J Org Chem. 2012 Nov 16;77(22):10468-72. doi: 10.1021/jo302005s. Epub 2012 Nov 7.

Abstract

An efficient Pd-catalyzed desulfitative coupling reaction of sodium arylsulfinates as arylation reagents by C-O bond cleavage of aryl triflates was developed. With only 2 mol % of Pd(OAc)(2) as catalyst and XPhos as ligand, the reaction proceeded well for a range of substrates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arylsulfonates / chemistry*
  • Catalysis
  • Ligands
  • Molecular Structure
  • Palladium / chemistry*
  • Sodium / chemistry*

Substances

  • Arylsulfonates
  • Ligands
  • Palladium
  • Sodium