p73 is dispensable for commitment to neural stem cell fate, but is essential for neural stem cell maintenance and for blocking premature differentiation

Cell Death Differ. 2013 Feb;20(2):368. doi: 10.1038/cdd.2012.134. Epub 2012 Oct 26.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Apoptosis
  • Cell Differentiation
  • Cells, Cultured
  • DNA-Binding Proteins / deficiency
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism*
  • Induced Pluripotent Stem Cells / cytology
  • Induced Pluripotent Stem Cells / metabolism
  • Intermediate Filament Proteins / genetics
  • Intermediate Filament Proteins / metabolism
  • Mice
  • Nerve Tissue Proteins / genetics
  • Nerve Tissue Proteins / metabolism
  • Nestin
  • Neural Stem Cells / cytology
  • Neural Stem Cells / metabolism*
  • Nuclear Proteins / deficiency
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism*
  • Tumor Protein p73
  • Tumor Suppressor Proteins / deficiency
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism*

Substances

  • DNA-Binding Proteins
  • Intermediate Filament Proteins
  • Nerve Tissue Proteins
  • Nes protein, mouse
  • Nestin
  • Nuclear Proteins
  • Trp73 protein, mouse
  • Tumor Protein p73
  • Tumor Suppressor Proteins