Assumptions in studies of heritability and genotype-phenotype association

Behav Brain Sci. 2012 Oct;35(5):372-3. doi: 10.1017/S0140525X12001380.

Abstract

Charney's dismissal of well-established methods in behavioral genetic research is misguided. He claims that studies of heritability and genetic association depend for their validity on six assumptions, but he cites no sources to support this claim. We explain why none of the six assumptions is strictly necessary for the utility of either method of genetic analysis.

Publication types

  • Comment

MeSH terms

  • Female
  • Genetics, Behavioral*
  • Genomics*
  • Humans
  • Pregnancy