Advances in the surgical treatment of morbid obesity

Mol Aspects Med. 2013 Feb;34(1):84-94. doi: 10.1016/j.mam.2012.10.006. Epub 2012 Oct 23.

Abstract

Due to the rapidly expanding prevalence of obesity, bariatric surgery is becoming an increasingly popular treatment option. Bariatric surgeries including Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) produce long-term weight loss and metabolic improvement, reducing mortality. This review discusses the important benefits and risks of RYGB and VSG, highlighting hypothesized mechanisms for these effects. We present data suggesting that VSG, albeit a newer procedure, may be as effective as RYGB with fewer adverse effects including less surgical risk, reduced nutritional deficiency, and less incidence of dumping syndrome. This may position VSG as an increasingly important procedure, particularly for the treatment of pediatric obesity.

Publication types

  • Review

MeSH terms

  • Bone Density
  • Dumping Syndrome / etiology
  • Dumping Syndrome / physiopathology
  • Gastrectomy / adverse effects
  • Gastrectomy / methods*
  • Gastric Bypass / adverse effects
  • Gastric Bypass / methods*
  • Gastroesophageal Reflux / etiology
  • Gastroesophageal Reflux / physiopathology
  • Humans
  • Hypoglycemia / etiology
  • Hypoglycemia / physiopathology
  • Morbidity
  • Obesity, Morbid / mortality
  • Obesity, Morbid / surgery*
  • Postoperative Care
  • Prevalence
  • Risk Factors
  • Treatment Outcome
  • Weight Loss