Abstract
A one-step oxidative fluorination for carbon-fluorine bond formation from well-defined nickel complexes with oxidant and aqueous fluoride is presented, which enables a straightforward and practical (18)F late-stage fluorination of complex small molecules with potential for PET imaging.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Fluorine / chemistry*
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Fluorine Radioisotopes
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Molecular Structure
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Nickel / chemistry*
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Organometallic Compounds / chemical synthesis
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Organometallic Compounds / chemistry*
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Oxidation-Reduction
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Positron-Emission Tomography*
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Water / chemistry
Substances
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Fluorine Radioisotopes
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Organometallic Compounds
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Water
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Fluorine
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Nickel