Dorsolateral frontal lobe epilepsy

J Clin Neurophysiol. 2012 Oct;29(5):379-84. doi: 10.1097/WNP.0b013e31826b3c7c.

Abstract

Dorsolateral frontal lobe seizures often present as a diagnostic challenge. The diverse semiologies may not produce lateralizing or localizing signs and can appear bizarre and suggest psychogenic events. Unfortunately, scalp electroencephalographic (EEG) and magnetic resonance imaging (MRI) are often unsatisfactory. It is not uncommon that these traditional diagnostic studies are either unhelpful or even misleading. In some cases, SPECT and positron emission tomography imaging can be an effective tool to identify the origin of seizures. However, these techniques and other emerging techniques all have limitations, and new approaches are needed to improve source localization.

Publication types

  • Review

MeSH terms

  • Adult
  • Anticonvulsants / therapeutic use
  • Brain Mapping* / methods
  • Brain Waves* / drug effects
  • Electroencephalography
  • Epilepsy, Frontal Lobe / diagnosis*
  • Epilepsy, Frontal Lobe / physiopathology
  • Epilepsy, Frontal Lobe / therapy
  • Female
  • Frontal Lobe / diagnostic imaging
  • Frontal Lobe / drug effects
  • Frontal Lobe / pathology
  • Frontal Lobe / physiopathology*
  • Frontal Lobe / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Neurosurgical Procedures
  • Periodicity
  • Positron-Emission Tomography
  • Predictive Value of Tests
  • Tomography, Emission-Computed, Single-Photon
  • Treatment Outcome

Substances

  • Anticonvulsants