Whole-genome-amplified DNA as a source for mutational analysis underestimates the frequency of mutations in pediatric acute myeloid leukemia

Leukemia. 2013 Feb;27(2):510-2. doi: 10.1038/leu.2012.250. Epub 2012 Aug 31.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • DNA Mutational Analysis / methods*
  • DNA, Neoplasm / genetics
  • Gene Amplification*
  • Genome, Human*
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Mutation Rate*
  • Nuclear Proteins / genetics
  • Nucleophosmin
  • Polymerase Chain Reaction
  • fms-Like Tyrosine Kinase 3 / genetics

Substances

  • DNA, Neoplasm
  • Nuclear Proteins
  • Nucleophosmin
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3