Thermophilic enrichment of microbial communities in the presence of the ionic liquid 1-ethyl-3-methylimidazolium acetate

J Appl Microbiol. 2012 Dec;113(6):1362-70. doi: 10.1111/jam.12002. Epub 2012 Oct 1.

Abstract

Aims: The aim of the study was to develop an approach to enrich ionic liquid tolerant micro-organisms that efficiently decompose lignocellulose in a thermophilic and high-solids environment.

Methods and results: High-solids incubations were conducted, using compost as an inoculum source, to enrich for thermophilic communities that decompose switchgrass in the presence of the ionic liquid 1-ethyl-3-methylimidazolium acetate ([C2mim][OAc]). Ionic liquid levels were increased from 0 to 6% on a total weight basis incrementally. Successful enrichment of a community that decomposed lignocellulose at 55°C in the presence of 6% [C2mim][OAc] was achieved, when the [C2mim][OAc] level was increased stepwise from 2% to 4% to 5% to 6%. Pyrosequencing results revealed a shift in the community and a sharp decrease in richness, when thermophilic conditions were applied.

Conclusions: A community tolerant to a thermophilic, high-solids environment containing 6% [C2mim][OAc] was enriched from compost. Gradually increasing [C2mim][OAc] concentrations allowed the community to adapt to [C2mim][OAc].

Significance and impact of the study: A successful approach to enrich communities that decompose lignocellulose under thermophilic high-solids conditions in the presence of elevated levels of [C2mim][OAc] has been developed. Communities yielded from this approach will provide resources for the discovery of enzymes and metabolic pathways relevant to biomass pretreatment and fuel production.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacteria / classification
  • Bacteria / metabolism
  • Biomass
  • DNA, Bacterial / isolation & purification
  • Hot Temperature
  • Imidazoles / chemistry*
  • Ionic Liquids / chemistry*
  • Lignin / metabolism*
  • Metagenome
  • Panicum / chemistry
  • Sequence Analysis, DNA
  • Soil
  • Soil Microbiology*

Substances

  • DNA, Bacterial
  • Imidazoles
  • Ionic Liquids
  • Soil
  • lignocellulose
  • Lignin
  • 1-ethyl-3-methylimidazolium