Prevention of mother-to-infant transmission of influenza during the postpartum period

Am J Perinatol. 2013 Mar;30(3):233-40. doi: 10.1055/s-0032-1323585. Epub 2012 Aug 27.

Abstract

Objectives: The optimal management of infants born to mothers with peripartum influenza infection is not known. The objective of this study is to describe our experience with a practice guideline that promotes rooming-in and breast-feeding and to determine whether infants managed in this way acquire influenza infection.

Study design: All mothers diagnosed with influenza infection within 8 days of delivery and their infants were included. Demographics, clinical characteristics, and outcome data were collected. Mothers were contacted at ~1 month after giving birth to determine if their infants had developed any signs suggestive of influenza infection.

Results: Forty-two women were diagnosed with peripartum influenza over the 2003 to 2005 and 2009 to 2010 seasons. Median onset of symptoms was 3 days before delivery, and median day of diagnosis was 1 day before delivery. The 42 infants had a median gestational age of 39 weeks; none were born earlier than 35 weeks. Ninety-five percent of the infants roomed-in with their mothers. Follow-up information was available on 95% of infants by 1 month; no infants had illness suggestive of influenza through the follow-up period.

Conclusion: A guideline for the management of infants born to mothers with peripartum influenza infection, based on attention to hand hygiene, antiviral treatment for mothers, and encouragement of rooming-in and breast-feeding, was not associated with mother-to-infant influenza transmission over three separate influenza seasons.

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use
  • Breast Feeding
  • Female
  • Hand Hygiene
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Influenza, Human / drug therapy
  • Influenza, Human / prevention & control
  • Influenza, Human / transmission*
  • Male
  • Postpartum Period*
  • Practice Guidelines as Topic*
  • Retrospective Studies
  • Rooming-in Care
  • Young Adult

Substances

  • Antiviral Agents