Pharmacodynamic effects of EV-077: results of an in vitro pilot investigation in healthy volunteers

J Thromb Thrombolysis. 2012 Oct;34(3):297-9. doi: 10.1007/s11239-012-0795-6.
No abstract available

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Atherosclerosis / blood
  • Atherosclerosis / drug therapy
  • Blood Platelets / metabolism*
  • Enzyme Inhibitors / administration & dosage
  • Enzyme Inhibitors / pharmacokinetics*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Platelet Activation / drug effects*
  • Platelet Aggregation Inhibitors / administration & dosage
  • Platelet Aggregation Inhibitors / pharmacokinetics*
  • Receptors, Thromboxane A2, Prostaglandin H2 / antagonists & inhibitors*
  • Receptors, Thromboxane A2, Prostaglandin H2 / metabolism
  • Thromboxane A2 / blood
  • Thromboxane-A Synthase / antagonists & inhibitors*

Substances

  • Enzyme Inhibitors
  • Platelet Aggregation Inhibitors
  • Receptors, Thromboxane A2, Prostaglandin H2
  • Thromboxane A2
  • Thromboxane-A Synthase