Guillain-Barré-like syndrome in a child with lead poisoning

Neuropediatrics. 2012 Aug;43(4):217-20. doi: 10.1055/s-0032-1321981. Epub 2012 Jun 30.

Abstract

Lead poisoning is a medical condition caused by increased levels of the heavy metal lead in the body, generally resulting from environmental exposure. Lead poisoning can cause a variety of symptoms which vary depending on the individual and the duration of lead exposure; lead poisoning is more noxious to children than adults, because it can damage the brain and nerve development of children.We report a case of lead poisoning in a 5-year-old girl caused by accidental ingestion of a metal ring. Simultaneously, the child showed anemia, encephalopathy, and peripheral neuropathy with albuminocytological dissociation mimicking Guillain-Barré syndrome.This case suggests that anemia with signs of peripheral and central nervous system damage could be considered as a possible manifestation of lead poisoning in children.

Publication types

  • Case Reports

MeSH terms

  • Anemia / etiology
  • Aspartic Acid / analogs & derivatives
  • Aspartic Acid / metabolism
  • Brain / metabolism
  • Brain / pathology
  • Child, Preschool
  • Choline / metabolism
  • Female
  • Guillain-Barre Syndrome / diagnosis
  • Guillain-Barre Syndrome / etiology*
  • Humans
  • Lead Poisoning / complications*
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Nerve Fibers, Myelinated / metabolism
  • Nerve Fibers, Myelinated / pathology
  • Peripheral Nervous System Diseases / etiology
  • Protons

Substances

  • Protons
  • Aspartic Acid
  • N-acetylaspartate
  • Choline