Long-term and high-frequency in-sewer monitoring opens up a broad range of possibilities to study (influences on) water quantity and quality variations. Using data from the Eindhoven wastewater system in The Netherlands both dry weather flow and wet weather flow situations have been studied. For approximately 160 dry weather days mean diurnal variations of flow and pollutant concentrations have been derived. For wet weather situations (≈ 40 storm events) peak load factors have been studied. Generally, peak load factors for all considered pollutant parameters are larger than one. Peak load factors for particulate matter are larger than for dissolved constituents. Also, the smallest catchment area consistently shows the largest mean peak factors and vice versa.