A study of aromatic hydrogen bonds of peptides with aromatic amino acid side-chains

Indian J Biochem Biophys. 2004 Aug;41(4):184-7.

Abstract

The importance of hydrogen bonding studies lies in their structural, biological and medicinal applications. Non-conventional hydrogen bonds are weak, but are found to play an important role in biological molecules. In view of their importance,a study of the aromatic hydrogen bonds in peptides with aromatic amino acid side chains was carried out. The results indicate a reasonable probability for their occurrence, thereby enumerating their distinct features.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids, Aromatic / chemistry*
  • Biochemistry / methods*
  • Computer Simulation
  • Crystallography, X-Ray / methods
  • Histidine / chemistry
  • Hydrogen Bonding*
  • Models, Molecular
  • Molecular Conformation
  • Peptides / chemistry*
  • Phenylalanine / chemistry
  • Probability
  • Static Electricity
  • Tyrosine / chemistry

Substances

  • Amino Acids, Aromatic
  • Peptides
  • Tyrosine
  • Phenylalanine
  • Histidine