A template-assembled synthetic U-quadruplex

Chembiochem. 2012 Sep 3;13(13):1865-8. doi: 10.1002/cbic.201200442. Epub 2012 Aug 13.

Abstract

Fo(u)r U: A lipophilic cavitand with four dinucleoside (uridine) residues has been synthesized and characterized. NMR spectroscopy evidence suggests the self-assembly of a U-quadruplex by the uracil nucleobases in organic solution under ambient conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ethers, Cyclic / chemistry*
  • G-Quadruplexes*
  • Magnetic Resonance Spectroscopy
  • Resorcinols / chemistry*
  • Uridine / chemistry*

Substances

  • Ethers, Cyclic
  • Resorcinols
  • cavitand
  • Uridine