Temporal interferon-gamma release response to Mycobacterium kansasii infection in an anorexia nervosa patient

J Med Microbiol. 2012 Nov;61(Pt 11):1617-1620. doi: 10.1099/jmm.0.042739-0. Epub 2012 Aug 2.

Abstract

Due to the differences in the management of Mycobacterium kansasii disease and tuberculosis, an accurate diagnosis is required. This report, which describes what we believe to be the first documented case of M. kansasii infection in a patient suffering from anorexia nervosa, sheds light on the possible occurrence of a non-tuberculous mycobacterial infection that can mimic tuberculosis, on the risk of a misleading interpretation of interferon-gamma release assays, and on the temporal response to these tests.

Publication types

  • Case Reports

MeSH terms

  • Anorexia Nervosa / complications*
  • Antibodies, Bacterial / blood
  • Antitubercular Agents / administration & dosage
  • Antitubercular Agents / therapeutic use
  • Ethambutol / administration & dosage
  • Ethambutol / therapeutic use
  • Female
  • Humans
  • Interferon-gamma / genetics
  • Interferon-gamma / metabolism*
  • Isoniazid / administration & dosage
  • Isoniazid / therapeutic use
  • Lung Diseases / complications
  • Lung Diseases / immunology
  • Lung Diseases / microbiology*
  • Lymphocytes / classification
  • Lymphocytes / physiology
  • Mycobacterium Infections, Nontuberculous / complications
  • Mycobacterium Infections, Nontuberculous / immunology
  • Mycobacterium Infections, Nontuberculous / microbiology*
  • Mycobacterium kansasii / isolation & purification*
  • Rifampin / administration & dosage
  • Rifampin / therapeutic use
  • Young Adult

Substances

  • Antibodies, Bacterial
  • Antitubercular Agents
  • Interferon-gamma
  • Ethambutol
  • Isoniazid
  • Rifampin