Abstract
The development of viral nanoparticles (VNP) displaying multiple copies of the buckyball (C(60)) and their photodynamic activity is described. VNP-C(60) conjugates were assembled using click chemistry. Cell uptake and cell killing using white light therapy and a prostate cancer cell line is demonstrated.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Cell Line, Tumor
-
Click Chemistry
-
Fullerenes / chemistry*
-
Fullerenes / pharmacology*
-
Humans
-
Photochemotherapy / methods*
-
Photosensitizing Agents / chemistry*
-
Photosensitizing Agents / pharmacology*
-
Viruses / chemistry*
Substances
-
Fullerenes
-
Photosensitizing Agents
-
fullerene C60