Draft genome sequence of the sponge-associated strain Bacillus atrophaeus C89, a potential producer of marine drugs

Fang Liu; Wei Sun; Fei Su; Kang Zhou; Zhiyong Li

doi:10.1128/JB.00835-12

Draft genome sequence of the sponge-associated strain Bacillus atrophaeus C89, a potential producer of marine drugs

J Bacteriol. 2012 Aug;194(16):4454. doi: 10.1128/JB.00835-12.

Authors

Fang Liu¹, Wei Sun, Fei Su, Kang Zhou, Zhiyong Li

Affiliation

¹ State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

Abstract

Bacillus atrophaeus C89, isolated from the marine sponge Dysidea avara, is a potential producer of bioactive compounds, such as neobacillamide A and bacillamide C. Here, we present a 4.2-Mb assembly of its genome. The nonribosomal peptide synthetases (NRPSs) make it possible to produce the bioactive compounds.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bacillus / genetics*
Bacillus / isolation & purification
Bacillus / metabolism
Biological Products / metabolism
DNA, Bacterial / chemistry*
DNA, Bacterial / genetics*
Dysidea / microbiology
Genome, Bacterial*
Molecular Sequence Data
Peptide Biosynthesis, Nucleic Acid-Independent
Peptide Synthases / genetics
Sequence Analysis, DNA*

Substances

Biological Products
DNA, Bacterial
Peptide Synthases
non-ribosomal peptide synthase

Associated data

GENBANK/AJRJ00000000