[Effect of the energy metabolism regulator Yantar-Antitox on the system of energy production in rat liver during experimental pathology of beta-oxidation]

Eksp Klin Farmakol. 2012;75(5):24-7.
[Article in Russian]

Abstract

Effects of the Yantar-Aantitox (succinic acid preparation) preparation on bioenergetic processes in mitochondria of rat liver during the experimental disorders of beta oxidation process evoked by 4-pentenoic acid have been studied. It is established that the course administration of Yantar-Antitox leads to normalization of disturbed bioenergetic processes in rat liver, which is due to stimulation of the rapid metabolic cluster of mitochondria.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Energy Metabolism / drug effects*
  • Fatty Acids, Monounsaturated / adverse effects
  • Liver / drug effects*
  • Liver / metabolism
  • Liver Diseases / drug therapy*
  • Liver Diseases / metabolism
  • Male
  • Mitochondria, Liver / drug effects*
  • Mitochondria, Liver / metabolism
  • Rats
  • Succinic Acid / administration & dosage*

Substances

  • Fatty Acids, Monounsaturated
  • Succinic Acid
  • 4-pentenoic acid