Abstract
This article reviews the familiality, linkage, candidate gene, and genomewide association studies of obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, and other anxiety disorders (ie, generalized anxiety disorder, separation anxiety disorder, social phobia, and specific phobia). Studies involving children and adolescents are highlighted. Clinical and research implications are discussed.
MeSH terms
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Anxiety Disorders / genetics*
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Biomedical Research
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Child
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Epigenomics
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Genes / genetics*
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Genetic Linkage
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Genome, Human
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Genotype
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Humans
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Membrane Proteins / genetics
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Nerve Tissue Proteins / genetics
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Pedigree
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Receptor, trkB / genetics
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Risk Factors
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Serotonin Plasma Membrane Transport Proteins / genetics
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Signal Transduction / physiology
Substances
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CNTNAP2 protein, human
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Membrane Proteins
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Nerve Tissue Proteins
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Serotonin Plasma Membrane Transport Proteins
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Receptor, trkB