Markers that differentiate early from late IBD

Abstract

The worldwide emergence of autoimmune and chronic disorders has become a substantial burden to our current healthcare system. The evidence that IBD can manifest at either an early or late stage of evolution poses some intriguing questions: are there any markers that differentiate early from late IBD? In this article we explore the current data to better understand if any of these genetic, serologic, clinical course and/or microbiota markers do indeed serve to differentiate early from late IBD.