Life threatening hyperkalemia in a neonate with pseudo-hypoaldosteronism

J Pak Med Assoc. 2012 Mar;62(3):287-8.

Abstract

Pseudohypoaldosteronism type 1 is a rare disorder characterized by renal resistance to aldosterone which may present with a salt wasting crisis in infancy. We report a neonate with hyponatremia, severe dehydration and refractory life threatening hyperkalemia who was treated with dietary sodium chloride supplementation, potassium binding resins and fluid replacement therapy which proved to be lifesaving.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Diagnosis, Differential
  • Fludrocortisone / therapeutic use
  • Fluid Therapy
  • Humans
  • Hyperkalemia / diagnosis*
  • Hyperkalemia / therapy*
  • Infant, Newborn
  • Male
  • Polystyrenes / therapeutic use
  • Pseudohypoaldosteronism / diagnosis*
  • Pseudohypoaldosteronism / therapy*
  • Sodium Bicarbonate / therapeutic use
  • Sodium Chloride / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Polystyrenes
  • Sodium Chloride
  • polystyrene sulfonic acid
  • Sodium Bicarbonate
  • Fludrocortisone