Abstract
Little data exist regarding the association of epicardial adipose tissue (EAT) and cardiovascular disease among HIV-infected persons. Among 213 HIV-infected men, there was a significant association between protease inhibitor use and increasing EAT volume. EAT was significantly associated with coronary artery calcium greater than 100. The elevated coronary artery disease risk in HIV-infected men may be partially explained by EAT associated with protease inhibitor use.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adipose Tissue / diagnostic imaging*
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Adult
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Calcinosis / diagnostic imaging*
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Coronary Artery Disease / complications
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Coronary Artery Disease / diagnostic imaging*
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Cross-Sectional Studies
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HIV Infections / complications
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HIV Infections / drug therapy*
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HIV Protease Inhibitors / therapeutic use*
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Humans
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Male
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Middle Aged
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Risk Factors
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Tomography, X-Ray Computed / methods