Abstract
In the presence of catalytic amount of copper iodide, a remote amide-assisted intramolecular arylation followed by alkylation leads to a general and flexible synthetic method toward the synthesis of medicinally interesting hexahydropyrroloindole alkaloids.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemical synthesis*
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Alkylation
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Anilides / chemistry*
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Bromine Compounds / chemistry*
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Catalysis
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Copper / chemistry*
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Hydroxylation
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Indoles / chemistry*
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Molecular Structure
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Pyrroles / chemistry*
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Stereoisomerism
Substances
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Alkaloids
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Anilides
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Bromine Compounds
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Indoles
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Pyrroles
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Copper
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indole