Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation

J Pharmacol Exp Ther. 1979 Oct;211(1):26-30.
No abstract available

MeSH terms

  • 3',5'-Cyclic-AMP Phosphodiesterases / antagonists & inhibitors*
  • 3',5'-Cyclic-AMP Phosphodiesterases / blood
  • 3',5'-Cyclic-GMP Phosphodiesterases / antagonists & inhibitors
  • Animals
  • Blood Platelets / drug effects
  • Blood Platelets / enzymology*
  • Cyclic AMP / biosynthesis
  • Cyclic AMP / blood
  • In Vitro Techniques
  • Platelet Aggregation / drug effects*
  • Quinolines / pharmacology*
  • Quinolones
  • Rabbits

Substances

  • Quinolines
  • Quinolones
  • cilostamide
  • Cyclic AMP
  • 3',5'-Cyclic-AMP Phosphodiesterases
  • 3',5'-Cyclic-GMP Phosphodiesterases