Beam-hardening correction for virtual monochromatic imaging of myocardial perfusion via fast-switching dual-kVp 64-slice computed tomography: a pilot study using a human heart specimen

Circ J. 2012;76(7):1799-801. doi: 10.1253/circj.cj-12-0463. Epub 2012 May 18.

Abstract

Background: Investigate the effectiveness of beam-hardening (BH) correction using ECG-gated dual-kVp computed tomography (CT) for myocardial imaging.

Methods and results: A human heart specimen and artificial descending aorta were scanned using both dual-kVp and single 120-kVp modes. The myocardial CT values at the anterior and posterobasal walls were 89.4±6.2 and 87.1±6.9 HU (P=0.59) for the 69-keV images, and 88.3±5.9 and 49.9±13.5 HU (P=0.002) for the 120-kVp images, respectively.

Conclusions: Fast-switching dual-kVp technology is feasible for the correction of CT value deficits induced by BH that mimics perfusion defects.

MeSH terms

  • Artifacts
  • Cardiac-Gated Imaging Techniques* / instrumentation
  • Electrocardiography
  • Feasibility Studies
  • Humans
  • Multidetector Computed Tomography* / instrumentation
  • Myocardial Perfusion Imaging / instrumentation
  • Myocardial Perfusion Imaging / methods*
  • Phantoms, Imaging
  • Pilot Projects
  • Predictive Value of Tests
  • Radiographic Image Interpretation, Computer-Assisted*