Vulvar and vaginal cancer

Obstet Gynecol Clin North Am. 2012 Jun;39(2):213-31. doi: 10.1016/j.ogc.2012.04.002.

Abstract

Vulvar cancer is becoming more common as the population ages and is primarily a disease of the elderly. Most vulvar cancers are diagnosed at a localized stage and can be cured with surgery and adjuvant radiotherapy. More conservative therapy has been the mainstay in vulvar cancer treatment, which has lessened short-term and long-term morbidity without sacrificing efficacy. Recent national and international studies continue to prove the value of sentinel lymph node technology, which is moving toward a new standard of care for women with early stage vulvar cancer. Vaginal cancer is a rare cancer that also affects elderly women. Prognosis is poor; however, adequate treatment can be delivered with a combination of external beam radiotherapy and brachytherapy, and with surgical resection for a select group of patients.

MeSH terms

  • Adult
  • Aged
  • Brachytherapy
  • Carcinoma, Basal Cell / epidemiology
  • Carcinoma, Basal Cell / pathology
  • Carcinoma, Basal Cell / therapy
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / therapy
  • Carcinoma, Verrucous / epidemiology
  • Carcinoma, Verrucous / pathology
  • Carcinoma, Verrucous / therapy
  • Female
  • Humans
  • Incidence
  • Lichen Planus / epidemiology
  • Lichen Planus / pathology
  • Lichen Planus / therapy
  • Lichen Sclerosus et Atrophicus / epidemiology
  • Lichen Sclerosus et Atrophicus / pathology
  • Lichen Sclerosus et Atrophicus / therapy
  • Melanoma / epidemiology
  • Melanoma / pathology
  • Melanoma / therapy
  • Middle Aged
  • Paget Disease, Extramammary / epidemiology
  • Paget Disease, Extramammary / pathology
  • Paget Disease, Extramammary / therapy
  • Prognosis
  • Radiotherapy, Adjuvant
  • Sentinel Lymph Node Biopsy
  • United States / epidemiology
  • Vaginal Neoplasms* / epidemiology
  • Vaginal Neoplasms* / pathology
  • Vaginal Neoplasms* / therapy
  • Vulvar Neoplasms* / epidemiology
  • Vulvar Neoplasms* / pathology
  • Vulvar Neoplasms* / therapy