Purpose: To compare the antimicrobial activity of Endocal, calcium hydroxide paste, Calxyl, Vitapex on Porphyromonas endodontalis(P.e).
Methods: (1) The antimicrobial activity of different calcium hydroxide on P.e was examined at different exposure times by dynamic nephelometry. (2) 85 freshly extracted single-rooted human teeth were selected and cut at the amelocemental junction. All roots were randomly divided into five groups. The bacteria were incubated in each canal and were sampled and counted before and after enveloping five kinds of intercanal medicine seeded. Student's t test, One-way ANOVA were used with SPSS11.0 software package for statistical analysis.
Results: The bacteria from each group were reduced significantly after intracanal medication (P<0.05). The antibacterial efficacy of Endocal and calcium hydroxide paste were superior to others under dynamic nephelometry test (P<0.05). Endocal, calcium hydroxide paste, Calxyl, Vitapex had strong inhibitory effect on P.e from infected root canals, and the rate of bacteria clearance was 95%. The antimicrobial activity of Endocal was significantly greater than others (P<0.05).
Conclusions: Endocal, calcium hydroxide paste, Calxyl and Vitapex were effective for intercanal disinfection. The antibacterial activity of Endocal is greater than Vitapex.