The prevalence of detrusor overactivity amongst patients with symptoms of overactive bladder: a retrospective cohort study

Int Urogynecol J. 2012 Nov;23(11):1577-80. doi: 10.1007/s00192-012-1781-4. Epub 2012 Apr 25.

Abstract

Introduction and hypothesis: Overactive bladder (OAB) is a symptom-based condition consisting of urgency, with or without incontinence, usually with frequency and nocturia. There are many potential causes of OAB, yet many patients are prescribed anticholinergic medications empirically. This study aimed to determine what proportion of patients presenting for urogynecologic assessment with symptoms of OAB had urodynamic detrusor overactivity (DO).

Methods: Retrospective chart review was performed for 220 consecutive patient referrals. Demographic data, physical exam information, and urodynamic results were collected. The t test and Fisher's exact test were used for statistical analyses.

Results: The prevalence of DO was 11.8 % in this population. Urogenital atrophy and incomplete emptying were more common. Patients with DO were older and more often menopausal than those without DO. Significant prolapse was a common finding amongst patients with OAB symptoms.

Conclusions: Patients with symptoms of OAB should undergo pelvic examination and assessment of post-void residuals before being initiated on anticholinergic medication.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cholinergic Antagonists / therapeutic use
  • Cohort Studies
  • Female
  • Gynecological Examination
  • Humans
  • Middle Aged
  • Muscle, Smooth / physiopathology*
  • Prevalence
  • Retrospective Studies
  • Urinary Bladder, Overactive / drug therapy
  • Urinary Bladder, Overactive / epidemiology*
  • Urinary Bladder, Overactive / physiopathology*
  • Urodynamics / physiology

Substances

  • Cholinergic Antagonists