Abstract
A novel approach for the direct C-4 arylation of N-methyl-1,2,3,4-tetrahydroisoquinolines by nucleophilic addition of β-aminocarbanions to benzynes is described which provides a one-pot procedure for synthesis of the title compounds.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Combinatorial Chemistry Techniques
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Molecular Structure
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Stereoisomerism
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Tetrahydroisoquinolines / chemical synthesis*
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Tetrahydroisoquinolines / chemistry