Dermoscopy of Merkel cell carcinoma

Dermatology. 2012;224(2):140-4. doi: 10.1159/000337411. Epub 2012 Apr 6.

Abstract

Introduction: Merkel cell carcinoma (MCC) is an aggressive cutaneous tumor whose clinical presentation, usually a pink nodule, is not specific. We aimed in this study to determine the dermoscopic criteria encountered in MCC.

Methods: From our image database we selected the patients diagnosed with MCC and scored the dermoscopic criteria shown by these tumors.

Results: Ten patients coming from three different academic hospitals were studied. Vascular structures were the more relevant dermoscopic features. In 8 out of 10 (80%) patients a polymorphic vascular pattern was seen, composed of milky-red clods/areas in association with one or more additional vascular structures.

Conclusion: Although an overlap existed between the dermoscopic features observed in MCC and amelanotic melanoma, the presence of a polymorphous vascular pattern may constitute an additional clinical clue to accurately diagnose this rare tumor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Merkel Cell / blood supply
  • Carcinoma, Merkel Cell / pathology*
  • Dermoscopy / methods*
  • Female
  • Humans
  • Male
  • Melanoma, Amelanotic / blood supply
  • Melanoma, Amelanotic / pathology*
  • Middle Aged
  • Pilot Projects
  • Skin Neoplasms / blood supply
  • Skin Neoplasms / pathology*