[Clinicopathological features of 8 patients with metastatic gastric tumors]

Nihon Shokakibyo Gakkai Zasshi. 2012 Apr;109(4):585-92.
[Article in Japanese]

Abstract

We examined the clinicopathological features of metastatic gastric tumor, using 9 tumors of 8 patients. Histological diagnosis with all biopsy specimens were adenocarcinoma. Most of the metastatic sites were located in the middle or upper gastric corpus. Endoscopic features of the lesion showed a submucosal tumor-like (5 cases) and primary gastric cancer-like (3 cases) appearance. Immunohistochemical staining of cytokeratins, TTF-1, surfactant protein, ER, or MGB1 identified the primary site; 6 in the lung and 2 in the breast. One case was diagnosed based on the EGFR mutation analysis. In conclusion, immunohistochemical staining and molecular method are useful tools to distinguish metastatic gastric tumor from primary gastric cancer.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma / pathology*
  • Adenocarcinoma / secondary*
  • Aged
  • Biopsy
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / secondary*