Behavioral bioassays and their uses in Tetrahymena

Methods Cell Biol. 2012:109:393-410. doi: 10.1016/B978-0-12-385967-9.00015-3.

Abstract

The swimming behaviors of Tetrahymena can be used in sensitive behavioral bioassays for estimating the effects of drugs, mutations, and other conditions on the physiological state of the cell. These assays can be used in both forward and reverse genetic approaches to help understand cellular functions from genotype to phenotype.

MeSH terms

  • Adaptation, Physiological
  • Biological Assay / methods*
  • Cell Survival
  • Chemotaxis
  • Cilia / physiology
  • Electrophysiological Phenomena
  • Genotype
  • Image Processing, Computer-Assisted
  • Mutation
  • Phenotype
  • Potassium / pharmacology
  • Reproduction
  • Swimming / physiology*
  • Tetrahymena / drug effects
  • Tetrahymena / growth & development
  • Tetrahymena / physiology*
  • Time Factors

Substances

  • Potassium