Ultrafast rotary PCR system for multiple influenza viral RNA detection

Lab Chip. 2012 May 7;12(9):1598-600. doi: 10.1039/c2lc21269b. Epub 2012 Mar 22.

Abstract

We presented a novel platform for an ultrafast PCR system, called the Rotary PCR Genetic Analyzer, which incorporates a thermal block and resistive temperature detector (RTD) for thermal cycling control, a disposable PCR microchip, and a stepper motor. The influenza viral RNAs from H3N2, H5N1, and H1N1 were simultaneously identified with high sensitivity and speed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Equipment Design
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics
  • Influenza A virus / classification
  • Influenza A virus / genetics
  • Influenza A virus / isolation & purification*
  • Lab-On-A-Chip Devices
  • RNA, Viral / analysis*
  • Reverse Transcriptase Polymerase Chain Reaction / instrumentation*
  • Reverse Transcriptase Polymerase Chain Reaction / methods*
  • Sensitivity and Specificity
  • Time Factors

Substances

  • Hemagglutinin Glycoproteins, Influenza Virus
  • RNA, Viral