Integration of proteomics into systems biology of cancer

Wiley Interdiscip Rev Syst Biol Med. 2012 Jul-Aug;4(4):327-37. doi: 10.1002/wsbm.1169. Epub 2012 Mar 8.

Abstract

Deciphering the complexity and heterogeneity of cancer, benefits from integration of proteomic level data into systems biology efforts. The opportunities available as a result of advances in proteomic technologies, the successes to date, and the challenges involved in integrating diverse datasets are addressed in this review.

Publication types

  • Review

MeSH terms

  • Humans
  • Mass Spectrometry
  • Neoplasms / metabolism*
  • Neoplasms / pathology
  • Protein Interaction Maps
  • Protein Modification, Translational
  • Proteome / analysis
  • Proteomics*
  • Signal Transduction
  • Systems Biology*

Substances

  • Proteome